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Laterality of pain in migraine distinguished by interictal rates of habituation of electrodermal responses to visual and auditory stimuli.

机译:偏头痛的偏侧性以对视觉和听觉刺激的电皮反应习惯化的发作间隔率来区分。

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摘要

Support is provided for a primary neural factor in migraine by studies in autonomic responsiveness to sensory stimuli in relation to the laterality of pain. Migraineurs with consistently lateralised headaches were found in two studies to exhibit extremes of autonomic responsiveness to sensory stimuli during the interictal phase. The direction of responsiveness was predictive of the laterality of pain; left-sided pain was associated with under-responsiveness and fast habituation, right-sided pain with over-responsiveness and slow habituation. Bipolarity in rate of habituation is consistent with a defect in a regulatory mechanism that controls regional cerebral activation such as the diffuse thalamic projection system.
机译:通过对与疼痛的偏侧性有关的对感觉刺激的自主反应的研究,为偏头痛中的主要神经因子提供了支持。在两项研究中发现偏头痛持续偏头痛的偏头痛患者在发作期表现出对感觉刺激的自主神经反应极端性。反应的方向预示着疼痛的程度。左侧疼痛与反应不足和快速适应有关,右侧疼痛与反应过度和缓慢适应有关。习惯性速率的双极性与控制局部脑部激活的调节机制(如弥漫性丘脑投射系统)中的缺陷一致。

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